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勃起障害に関する記事ですね。 ---------------------------------------- In order to establish and maintain an erection, several neurotransmitters must be provided to the arterial and venous structures of the penis1-15. The primary neurotransmitters that operate to dilate penile arteries and constrict penile veins are nitric oxide10; 11; 16-38 and acetylcholine39-45.
Both nitric oxide and acetylcholine function to increase intracellularGMP. Inhibition of GMP degradation is an important treatment for various forms of erectile dysfunction12; 15; 30; 46-69.The pharmaceutical sildenafil functions by inhibiting GMP10; 14; 50; 52; 53; 56; 69-84. Thus,activation of nitric oxide, activation of acetylcholine, inhibition of norepinephrine, and inhibiting GMP are necessary for production and maintenance of erection. --------------------------------------- 【簡約】
